There are two main types of lung cancer: non-small cell lung cancer (NSCLC) and small-cell lung cancer (SCLC). SCLC makes up about 15% of lung cancer cases.
SCLC is a fast-growing cancer that develops when a specific type of lung cell, called a neuroendocrine cell, grows out of control.
Patients with SCLC are often diagnosed after the cancer has reached an advanced stage because symptoms don't typically appear early in the disease.
The stage of the cancer, or how far it has spread, will determine whether you have limited-stage or extensive-stage disease. The stage of the cancer will also affect your treatment options. Most patients have extensive-stage disease at the time of diagnosis.
Limited-stage cancer is often treated with surgery, radiation, and/or chemotherapy, while extensive-stage SCLC requires chemotherapy and sometimes immunotherapy. Extensive-stage SCLC has a high rate of returning after the first treatment.
Clinical trials may be an option for patients with SCLC.
To determine if you may be eligible for a clinical trial for tarlatamab, talk to your doctor or contact an Amgen Medical Information Healthcare Professional.
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What is the DeLLphi-305 Clinical Trial?
For patients with extensive-stage SCLC receiving their first course of treatment. Patients with prior limited-stage SCLC may qualify.
What is the DeLLphi-306 Clinical Trial?
For patients with limited-stage SCLC who have completed chemotherapy and radiation therapy without progression.